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STEMThe E2 protein scaffold represents a versatile antigen delivery system (ESTEMThe E2 protein scaffold represents a versatile antigen delivery system (E2DISP) where antigenic determinants can be exposed on the surface of an icosahedral [61,62] dodecahedral nanoparticle . The scaffold is composed of the E2 acetyltransferase protein derived from the pyruvate dehydrogenase (PDH) multienzyme c

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